There are several reasons why heart disease risk may increase with age, including arteriosclerosis, or a stiffening of blood vessels.
Past studies show that making certain healthy lifestyle changes may help reduce a person’s risk of developing cardiovascular disease as they age, such as eating a heart-healthy diet.
A new study has found that a multi-ingredient longevity supplement may help improve markers of vascular aging, including arterial flexibility and healthy blood pressure support.
Supplement helps improve endothelial function, arterial flexibility
At the study’s conclusion, researchers found that participants taking NOVOS Core experienced a measurable improvement in the function of their endothelial cells — which line the inside of blood vessels — shortly after the first dose, and this improvement persisted for 6 months.
“The significance is twofold,” Heiss explained. “First, the early response suggests the intervention can influence vascular function quickly, consistent with effects on endothelial signalling/vasoreactivity. Second, the fact that benefit was still present at six months — measured ~24 hours after the last dose — suggests more than a transient ‘short-lived’ effect and is compatible with longer-term improvement in vascular health.”
Scientists also found participants taking the supplement experienced improved arterial flexibility — or pulse wave velocity (PWV) — compared to placebo at six months, as well as better systolic blood pressure.
“PWV is a widely used marker of arterial stiffness, a core feature of vascular aging, and systolic blood pressure is a major determinant of cardiovascular risk over time,” Heiss explained. “In our trial, after six months, the supplement arm showed a greater reduction in PWV versus control and a clinically meaningful lowering of systolic blood pressure, alongside the endothelial improvements.”